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Vol. 71 Br. 8 (2014)
Vol. 71 Br. 8 (2014)

Nesimptomatični tok bolesti Rosai-Dorfman

DOI: 10.2298/2342
Dragan Petrović
Department of Maxillofacial Surgery, Clinic of Stomatology, Faculty of Medicine, University of Niš, Niš, Serbia
Dragan Mihailović
Department of Pathology, Clinic of Stomatology, Faculty of Medicine, University of Niš, Niš, Serbia
Sladjana Petrović
Department of Radiology, Clinic of Stomatology, Faculty of Medicine, University of Niš, Niš, Serbia
Nikola Živković
Department of Pathology, Clinic of Stomatology, Faculty of Medicine, University of Niš, Niš, Serbia
Žaklina Mijović
Department of Pathology, Clinic of Stomatology, Faculty of Medicine, University of Niš, Niš, Serbia
Bojko Bjelaković
Department of Pediatrics, Clinic of Stomatology, Faculty of Medicine, University of Niš, Niš, Serbia
Miloš Kostić
Department of Immunology, Clinic of Stomatology, Faculty of Medicine, University of Niš, Niš, Serbia
Ljiljana Kesić
Department of Oral Medicine, Clinic of Stomatology, Faculty of Medicine, University of Niš, Niš, Serbia
Ana Stanković
Clinic of Oncology, Clinical Center of Niš, Serbia
Milica Petrović
Department of Oral Medicine, Clinic of Stomatology, Faculty of Medicine, University of Niš, Niš, Serbia
Ivica Vučković
Department of Maxillofacial Surgery, Clinic of Stomatology, Faculty of Medicine, University of Niš, Niš, Serbia
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Objavljeno

2014-07-30

Sekcija

Prikaz bolesnika

Kako citirati

1.
Petrović D, Mihailović D, Petrović S, Živković N, Mijović Žaklina, Bjelaković B, i drugi. Nesimptomatični tok bolesti Rosai-Dorfman. Vojnosanit Pregl [Internet]. 30. Juli 2014. [citirano 12. Juli 2026.];71(8). Dostupno na: https://asistent.ceon.rs/index.php/vsp/article/view/VSP1408780P
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Sažetak

Uvod. Sinusna histiocitoza sa masivnom limfadenopatijom je retka benigna bolest nepoznate etiologije. Zahvaćenost pljuvačnih žlezda ukazuje na ekstramodularni karakter bolesti i često zahvata imunohistohemijsko bojenje hirurški odstranjenog tumora za potvrdu dijagnoze. Prikaz bolesnika. U radu je prikazan bolesnik, star 43 godine, sa bezbolnim tumorom u predelu levog ugla donje vilice. Kliničkim pregledom ustanovljena je bezbolna, pokretna, elastična čvoričasta struktura, promera 4 × 3 cm sa neizmenjenom kožom. Promena istih karakteristika, promera 2 × 2 cm, takođe je primećena u desnoj parotidnoj regiji. Regionalni limfni nodusi su bili urednog izgleda. Makroskopski, promena je bila čvrste konzistencije, kružna, multilobulirana, žućkaste prebojenosti. Mikroskopski, promena je bila uglavnom izgrađena od histiocita svetle citoplazme sa emperipolezom, plazma ćelija i limfocita, koji su bili raspoređeni difuzno i u grupama. Imunohistohemijski, histiociti su bili CD68 i S 100 protein pozitivni. Zaključak. Rosai-Dorfman je benigna bolest, na koju se često ne misli, te može biti pogrešno interpretirana kao neoplastična bolest.

Ključne reči

histiocytosis
sinus||
||histiocitoza
sinusna
diagnosis
differential||
||dijagnoza
diferencijalna
immunohistochemistry||
||imunohistohemija
treatment outcome||
||lečenje
ishod
DOI: 10.2298/2342

Reference

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