IMMUNOPOSITIVE NEURONS MORPHOLOGY OF SUBSTANCE P IN THE HUMAN PARIETAL LOBULE CORTEX

Abstract

ABSTRACT

This investigation has been provided in order to find out is there any particular connection between the neuronal body shapes and their immunoreactivity. Substance P (SP) neuropeptide was examined. The largest somata were obtained among SP positive neurons: average diameters (± SD) were: longer diameter 44.93 ± 15.69 m, shorter diameter 18.16 ± 3.77 m. One-way analysis of variance (O-ANOVA) revealed the highly significant difference among longer axis of immunopositive neurons (p=0.002). Most of the detected neurons (25%) were localized in lamina II of the LPI cortex. The least populated layer was lamina I (less than 10% of all immunoreactive neurons).

Key words: parietal cortex, neuropeptide, substance P, and laminar distribution